What is the official name of the EXT1 gene?
The official name of this gene is “exostoses (multiple) 1.”
EXT1 is the gene's official symbol.
The EXT1 gene is also known by other names, listed below.
What is the normal function of the EXT1 gene?
The EXT1 gene provides instructions for producing a protein called exostosin-1.
This protein is found in a cell structure called the Golgi apparatus, which modifies newly produced enzymes and other proteins.
In the Golgi apparatus, exostosin-1 attaches (binds) to another protein, exostosin-2, to form a complex that modifies a protein called heparan sulfate so it can be used in the body. Heparan sulfate is involved in regulating a variety of body processes including the formation of blood vessels (angiogenesis) and blood clotting. It also has a role in the spreading (metastasis) of cancer cells.
Continua el articulo, en versión Inglesa.